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    • Peer reviewed
    • Journal Article, Academic Journal
    Rifamycin antibiotics are commonly used for treatment of tuberculosis, but may reduce the effectiveness of hormonal contraception (HC).
    Subjects:
    • Peer reviewed
    • Academic Journal
    Background: Rifamycin antibiotics are commonly used for treatment of tuberculosis, but may reduce the effectiveness of hormonal contraception (HC).Objectives: To determine whether interactions between rifamycins and HC result in decreased effectiveness or increased toxicity of either t...
    Subjects:
    • Peer reviewed
    • Academic Journal
    Antimicrobial agents are widely used, and drug interactions are challenging due to increased risk of adverse effects or reduced efficacy. Among the interactions, the most important are those affecting metabolism, although those involving drug transporters are becoming increasingly known. T...
    Subjects:
    • Peer reviewed
    • Academic Journal
    Rifampin is a crucial antibiotic in the management of prosthetic joint infections (PJI), particularly due to its effectiveness against staphylococcal bacteria and its ability to penetrate and disrupt biofilms. This review evaluates rifampin's role by examining its mechanism of action, clinical efficacy, and inte...
    Subjects:
    • Peer reviewed
    • Academic Journal
    Objective: The purpose of this study was to determine whether interactions between non-rifamycin antibiotics and hormonal contraceptives result in decreased effectiveness or increased toxicity of either therapy.Study Design: We searched MEDLINE, Embase, clinicaltrials.gov, and Cochrane lib...
    Subjects:
    • Peer reviewed
    • Academic Journal
    The scale‐up of rifampicin‐based prevention regimens is an essential part of the global leprosy strategy. Daily rifampicin may reduce the effectiveness of the oral contraceptive pill (OCP), but little is known about the effects of rifampicin at the less frequent dosing intervals used for leprosy prophylaxis. ...
    Subjects:
    • Peer reviewed
    • Academic Journal
    Results of a new systematic literature review suggest that existing evidence does not support drug interactions between hormonal contraceptives and non-rifamycin antibiotics. The review should help clear misconceptions regarding hormonal contraception and drug interactions; for example, a maj...
    Subjects:
    • Peer reviewed
    • Academic Journal
    For early and long-term patient and graft survival, drug therapy in solid organ and hematopoietic stem cell transplantation inevitably involves polypharmacy in patients with widely varying and even abruptly changing conditions. In this second part, relevant medication briefing is provided, in addition to...
    Subjects:
    • Peer reviewed
    • Academic Journal
    Introduction: During the process of drug use, it is demanding to establish an effective and safe therapeutic scheme, especially in elderly patients, because they are polymedicated. In this sense, while the number of medications increases also increases the likelihood of the appearance of an interacti...